Prerequisites
You must have access to the Bazefield web server to resolve this issue.
Problem
Attempting to load any web page from the Bazefield web server fails with an HTTP 500 error:
Calling LoadLibraryEx on ISAPI filter "C:\Windows\Microsoft.NET\Framework\v4.0.30319\\aspnet_filter.dll" failed
This is more likely to occur on new installations.
Resolution
Step 1: Navigate to the ISAPI Filters section of IIS Manager
IIS Manager -> Top server level -> ISAPI Filters

Step 2: Remove the extra backslash in the executable path

Background
Depending on how the installation is done, an extra backslash may be added to the aspnet_filter.dll path which prevents IIS from finding it.
Product Environment and Version
Bazefield Portal 8.0.14